4pl4

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'''Unreleased structure'''
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==Crystal structure of murine IRE1 in complex with OICR464 inhibitor==
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<StructureSection load='4pl4' size='340' side='right' caption='[[4pl4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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The entry 4pl4 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4pl4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PL4 FirstGlance]. <br>
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Authors: Sanches, M., Duffy, N., Talukdar, M., Thevakumaran, N., Chiovitti, D., Al-awar, R., Patterson, J.B., Sicheri, F.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=31K:2-METHOXY-6-METHYL-4-(4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)PHENOL'>31K</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEU:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL'>PEU</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pl3|4pl3]], [[4pl5|4pl5]]</td></tr>
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Description:
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pl4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pl4 RCSB], [http://www.ebi.ac.uk/pdbsum/4pl4 PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Al-awar, R.]]
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[[Category: Chiovitti, D.]]
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[[Category: Duffy, N.]]
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[[Category: Patterson, J B.]]
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[[Category: Sanches, M.]]
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[[Category: Sicheri, F.]]
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[[Category: Talukdar, M.]]
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[[Category: Thevakumaran, N.]]
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[[Category: Endoribonuclease]]
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[[Category: Inhibitor complex]]
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[[Category: Schiff base]]
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[[Category: Unfolded protein response]]

Revision as of 06:10, 4 September 2014

Crystal structure of murine IRE1 in complex with OICR464 inhibitor

4pl4, resolution 3.00Å

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