User:Avinash S. Punekar/Sandbox 1

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=== Introduction ===
=== Introduction ===
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Post-transcriptional modification of ribosomal RNA (rRNA) occurs in all living organisms. In bacteria, rRNA modifications are done by site-specific enzymes. One such rRNA modification enzyme is a S-adenosyl-L-methionine (SAM) dependent methyltransferase RlmJ.
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Post-transcriptional modification of ribosomal RNA (rRNA) occurs in all living organisms. In bacteria, rRNA modifications are done by site-specific enzymes. One such rRNA modification enzyme is a S-adenosyl-L-methionine (SAM) dependent methyltransferase RlmJ. The biochemical experiments showed that the ''Escherichia coli'' RlmJ transfers a methyl group from SAM to the exocyclic nitrogen N6 of adenosine A2030 (m6A2030) in the 23S rRNA.
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<StructureSection load='4blu' size='340' side='right' caption='Methyltransferase RlmJ' scene=''>
<StructureSection load='4blu' size='340' side='right' caption='Methyltransferase RlmJ' scene=''>

Revision as of 13:04, 7 September 2014

Introduction

Post-transcriptional modification of ribosomal RNA (rRNA) occurs in all living organisms. In bacteria, rRNA modifications are done by site-specific enzymes. One such rRNA modification enzyme is a S-adenosyl-L-methionine (SAM) dependent methyltransferase RlmJ. The biochemical experiments showed that the Escherichia coli RlmJ transfers a methyl group from SAM to the exocyclic nitrogen N6 of adenosine A2030 (m6A2030) in the 23S rRNA.

Methyltransferase RlmJ

Drag the structure with the mouse to rotate

References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

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Avinash S. Punekar

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