4g6o
From Proteopedia
(Difference between revisions)
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<StructureSection load='4g6o' size='340' side='right' caption='[[4g6o]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4g6o' size='340' side='right' caption='[[4g6o]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4g6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4g6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G6O FirstGlance]. <br> |
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E28:4-{4-[4-(AMINOMETHYL)-3-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-YL}-N-(2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHYL)-1H-PYRROLE-2-CARBOXAMIDE'>E28</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br> | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E28:4-{4-[4-(AMINOMETHYL)-3-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-YL}-N-(2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHYL)-1H-PYRROLE-2-CARBOXAMIDE'>E28</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fux|4fux]], [[4fuy|4fuy]], [[4fv0|4fv0]], [[4fv1|4fv1]], [[4fv2|4fv2]], [[4fv3|4fv3]], [[4fv4|4fv4]], [[4fv5|4fv5]], [[4fv6|4fv6]], [[4fv7|4fv7]], [[4fv8|4fv8]], [[4fv9|4fv9]], [[4g6n|4g6n]]</td></tr> | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fux|4fux]], [[4fuy|4fuy]], [[4fv0|4fv0]], [[4fv1|4fv1]], [[4fv2|4fv2]], [[4fv3|4fv3]], [[4fv4|4fv4]], [[4fv5|4fv5]], [[4fv6|4fv6]], [[4fv7|4fv7]], [[4fv8|4fv8]], [[4fv9|4fv9]], [[4g6n|4g6n]]</td></tr> | ||
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERK2, MAPK1, PRKM1, PRKM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERK2, MAPK1, PRKM1, PRKM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g6o RCSB], [http://www.ebi.ac.uk/pdbsum/4g6o PDBsum]</span></td></tr> | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g6o RCSB], [http://www.ebi.ac.uk/pdbsum/4g6o PDBsum]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
| - | [[Category: Crystallographers, Vertex.]] | ||
[[Category: Kang, Y N.]] | [[Category: Kang, Y N.]] | ||
[[Category: Stuckey, J A.]] | [[Category: Stuckey, J A.]] | ||
| + | [[Category: Xie, X.]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 05:23, 24 September 2014
Crystal Structure of the ERK2
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