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2mg8

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==Molecular Binding of TFF1 Estrogen Response Element by a DNA Bis-intercalating Anticancer Drug XR5944==
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==Solution structure of TFF1 Estrogen Response Element complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944)==
<StructureSection load='2mg8' size='340' side='right' caption='[[2mg8]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''>
<StructureSection load='2mg8' size='340' side='right' caption='[[2mg8]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mg8]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MG8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mg8]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MG8 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XR2:1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM'>XR2</scene><br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XR2:1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM'>XR2</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x95|1x95]]</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mg8 RCSB], [http://www.ebi.ac.uk/pdbsum/2mg8 PDBsum]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mg8 RCSB], [http://www.ebi.ac.uk/pdbsum/2mg8 PDBsum]</span></td></tr>
<table>
<table>
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Solution structure of a 2:1 complex of anticancer drug XR5944 with TFF1 estrogen response element: insights into DNA recognition by a bis-intercalator.,Lin C, Mathad RI, Zhang Z, Sidell N, Yang D Nucleic Acids Res. 2014 Apr 7. PMID:24711371<ref>PMID:24711371</ref>
Solution structure of a 2:1 complex of anticancer drug XR5944 with TFF1 estrogen response element: insights into DNA recognition by a bis-intercalator.,Lin C, Mathad RI, Zhang Z, Sidell N, Yang D Nucleic Acids Res. 2014 Apr 7. PMID:24711371<ref>PMID:24711371</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==

Revision as of 05:56, 24 September 2014

Solution structure of TFF1 Estrogen Response Element complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944)

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