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4fv7

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<StructureSection load='4fv7' size='340' side='right' caption='[[4fv7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4fv7' size='340' side='right' caption='[[4fv7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fv7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FV7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fv7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FV7 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E94:4-(3-CHLOROPHENYL)-5-{2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}-2-{[2-(PIPERIDIN-1-YL)ETHYL]AMINO}THIOPHENE-3-CARBONITRILE'>E94</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E94:4-(3-CHLOROPHENYL)-5-{2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}-2-{[2-(PIPERIDIN-1-YL)ETHYL]AMINO}THIOPHENE-3-CARBONITRILE'>E94</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fux|4fux]], [[4fuy|4fuy]], [[4fv0|4fv0]], [[4fv1|4fv1]], [[4fv2|4fv2]], [[4fv3|4fv3]], [[4fv4|4fv4]], [[4fv5|4fv5]], [[4fv6|4fv6]], [[4fv8|4fv8]], [[4fv9|4fv9]]</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fux|4fux]], [[4fuy|4fuy]], [[4fv0|4fv0]], [[4fv1|4fv1]], [[4fv2|4fv2]], [[4fv3|4fv3]], [[4fv4|4fv4]], [[4fv5|4fv5]], [[4fv6|4fv6]], [[4fv8|4fv8]], [[4fv9|4fv9]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERK2, MAPK1, PRKM1, PRKM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERK2, MAPK1, PRKM1, PRKM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fv7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fv7 RCSB], [http://www.ebi.ac.uk/pdbsum/4fv7 PDBsum]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fv7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fv7 RCSB], [http://www.ebi.ac.uk/pdbsum/4fv7 PDBsum]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Kang, Y N.]]
[[Category: Kang, Y N.]]
[[Category: Stuckey, J A.]]
[[Category: Stuckey, J A.]]
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[[Category: Vertex-Crystallographers]]
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[[Category: Xie, X.]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 06:51, 24 September 2014

Crystal Structure of the ERK2 complexed with E94

4fv7, resolution 1.90Å

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