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1egk

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[[Image:1egk.gif|left|200px]]<br /><applet load="1egk" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1egk.gif|left|200px]]
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caption="1egk, resolution 3.1&Aring;" />
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'''CRYSTAL STRUCTURE OF A NUCLEIC ACID FOUR-WAY JUNCTION'''<br />
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{{Structure
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|PDB= 1egk |SIZE=350|CAPTION= <scene name='initialview01'>1egk</scene>, resolution 3.1&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURE OF A NUCLEIC ACID FOUR-WAY JUNCTION'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1EGK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGK OCA].
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1EGK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGK OCA].
==Reference==
==Reference==
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Alternative conformations of a nucleic acid four-way junction., Nowakowski J, Shim PJ, Stout CD, Joyce GF, J Mol Biol. 2000 Jun 30;300(1):93-102. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10864501 10864501]
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Alternative conformations of a nucleic acid four-way junction., Nowakowski J, Shim PJ, Stout CD, Joyce GF, J Mol Biol. 2000 Jun 30;300(1):93-102. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10864501 10864501]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Joyce, G F.]]
[[Category: Joyce, G F.]]
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[[Category: rna-dna complex]]
[[Category: rna-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:27:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:55:18 2008''

Revision as of 08:55, 20 March 2008

Image:1egk.gif


PDB ID 1egk

Drag the structure with the mouse to rotate
, resolution 3.1Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF A NUCLEIC ACID FOUR-WAY JUNCTION


Overview

A crystal structure of a 108 nucleotide RNA-DNA complex containing a four-way junction was solved at 3.1 A resolution. The structure of the junction differs substantially from the "stacked-X" conformation observed previously, due to a 135 degrees rotation of the branches. Comparison of the two conformers provides insight into the factors contributing to the flexibility of four-way junctions. The stacked-X conformation maximizes base-stacking but causes unfavorable repulsion between phosphate groups, whereas the 135 degrees -rotated "crossed" conformation minimizes electrostatic clashes at the expense of reduced base-stacking. Despite the large rotation of the branches, both junction structures exhibit an antiparallel arrangement of the continuous strands and opposite polarity of the crossover strands.

About this Structure

1EGK is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Alternative conformations of a nucleic acid four-way junction., Nowakowski J, Shim PJ, Stout CD, Joyce GF, J Mol Biol. 2000 Jun 30;300(1):93-102. PMID:10864501

Page seeded by OCA on Thu Mar 20 10:55:18 2008

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