3rvb

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'''Unreleased structure'''
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==The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479==
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<StructureSection load='3rvb' size='340' side='right' caption='[[3rvb]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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The entry 3rvb is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rvb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RVB FirstGlance]. <br>
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Authors: Mather, O., Cheng, R., Schonfield, D., Barker, J.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=I79:{1-[(5-CHLORO-2-METHYL-1-BENZOTHIOPHEN-3-YL)METHYL]-6-(3,5-DIAMINOPHENYL)-1H-INDOL-3-YL}ACETIC+ACID'>I79</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
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Description: The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rvb RCSB], [http://www.ebi.ac.uk/pdbsum/3rvb PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: RNA helicase]]
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[[Category: Barker, J.]]
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[[Category: Cheng, R.]]
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[[Category: Mather, O.]]
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[[Category: Schonfield, D.]]
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[[Category: Atp hydrolysis]]
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[[Category: Helicase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 10:38, 24 September 2014

The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479

3rvb, resolution 2.20Å

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