1eu0

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{{Theoretical_model}}
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==THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)==
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<StructureSection load='1eu0' size='340' side='right' caption='[[1eu0]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EU0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eu0 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eu0 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Involucrin is a key component of the cross-linked envelope of terminally differentiated keratinocytes. The human molecule largely consists of 10 residue repeats and forms a thin 460 A long rod. Summarized experimental data and a detailed stereochemical analysis made with computer modeling resulted in a structural model for the involucrin molecule. The suggested structure is a left-handed alpha-helical solenoid built of a tandem array of helix-turn-helix folds. The structure enables us to explain the whole set of experimental data and residue conservations within the repeats. It is ideally suited to serve as a scaffold for cell envelope assembly and proposes a possible mode of the intermolecular interactions of involucrin during cell cornification.
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[[Image:1eu0.png|left|200px]]
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alpha-Helical solenoid model for the human involucrin.,Kajava AV FEBS Lett. 2000 May 12;473(2):127-31. PMID:10812058<ref>PMID:10812058</ref>
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{{STRUCTURE_1eu0| PDB=1eu0 | SCENE= }}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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===THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)===
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_10812058}}
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:010812058</ref><references group="xtra"/>
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[[Category: Kajava, A V]]
[[Category: Kajava, A V]]

Revision as of 11:32, 24 September 2014

THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)

1eu0

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