1ey1
From Proteopedia
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| - | [[Image:1ey1.jpg|left|200px]] | + | [[Image:1ey1.jpg|left|200px]] |
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| - | '''SOLUTION STRUCTURE OF ESCHERICHIA COLI NUSB''' | + | {{Structure |
| + | |PDB= 1ey1 |SIZE=350|CAPTION= <scene name='initialview01'>1ey1</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''SOLUTION STRUCTURE OF ESCHERICHIA COLI NUSB''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1EY1 is a [ | + | 1EY1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EY1 OCA]. |
==Reference== | ==Reference== | ||
| - | The structure of the transcriptional antiterminator NusB from Escherichia coli., Altieri AS, Mazzulla MJ, Horita DA, Coats RH, Wingfield PT, Das A, Court DL, Byrd RA, Nat Struct Biol. 2000 Jun;7(6):470-4. PMID:[http:// | + | The structure of the transcriptional antiterminator NusB from Escherichia coli., Altieri AS, Mazzulla MJ, Horita DA, Coats RH, Wingfield PT, Das A, Court DL, Byrd RA, Nat Struct Biol. 2000 Jun;7(6):470-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10881193 10881193] |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: transcirption termination]] | [[Category: transcirption termination]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:01:45 2008'' |
Revision as of 09:01, 20 March 2008
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SOLUTION STRUCTURE OF ESCHERICHIA COLI NUSB
Overview
We have determined the solution structure of NusB, a transcription antitermination protein from Escherichia coli. The structure reveals a novel, all alpha-helical protein fold. NusB mutations that cause a loss of function (NusB5) or alter specificity for RNA targets (NusB101) are localized to surface residues and likely affect RNA-protein or protein-protein interactions. Residues that are highly conserved among homologs stabilize the protein core. The solution structure of E. coli NusB presented here resembles that of Mycobacterium tuberculosis NusB determined by X-ray diffraction, but differs substantially from a solution structure of E. coli NusB reported earlier.
About this Structure
1EY1 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
The structure of the transcriptional antiterminator NusB from Escherichia coli., Altieri AS, Mazzulla MJ, Horita DA, Coats RH, Wingfield PT, Das A, Court DL, Byrd RA, Nat Struct Biol. 2000 Jun;7(6):470-4. PMID:10881193
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