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1ih6

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[[Image:1ih6.png|left|200px]]
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==Multi-Conformation Crystal Structure of GGBr5CGCC==
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<StructureSection load='1ih6' size='340' side='right' caption='[[1ih6]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ih6]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IH6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ih1|1ih1]], [[1ih2|1ih2]], [[1ih3|1ih3]], [[1ih4|1ih4]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ih6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ih6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ih6 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway.
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{{STRUCTURE_1ih6| PDB=1ih6 | SCENE= }}
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A crystallographic map of the transition from B-DNA to A-DNA.,Vargason JM, Henderson K, Ho PS Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:11390969<ref>PMID:11390969</ref>
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===Multi-Conformation Crystal Structure of GGBr5CGCC===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_11390969}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1ih6]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH6 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:011390969</ref><references group="xtra"/>
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[[Category: Henderson, K.]]
[[Category: Henderson, K.]]
[[Category: Ho, P S.]]
[[Category: Ho, P S.]]

Revision as of 14:33, 28 September 2014

Multi-Conformation Crystal Structure of GGBr5CGCC

1ih6, resolution 1.45Å

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