1odv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1odv" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:1odv.png|left|200px]]
+
==PHOTOACTIVE YELLOW PROTEIN 1-25 DELETION MUTANT==
 +
<StructureSection load='1odv' size='340' side='right' caption='[[1odv]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1odv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ODV FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene><br>
 +
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d7e|1d7e]], [[1f98|1f98]], [[1f9i|1f9i]], [[1gsv|1gsv]], [[1gsw|1gsw]], [[1gsx|1gsx]], [[1kou|1kou]], [[1nwz|1nwz]], [[2phy|2phy]], [[2pyp|2pyp]], [[2pyr|2pyr]], [[3phy|3phy]], [[3pyp|3pyp]]</td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1odv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1odv RCSB], [http://www.ebi.ac.uk/pdbsum/1odv PDBsum]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/1odv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
PAS (PER-ARNT-SIM) domains are a family of sensor protein domains involved in signal transduction in a wide range of organisms. Recent structural studies have revealed that these domains contain a structurally conserved alpha/beta-fold, whereas almost no conservation is observed at the amino acid sequence level. The photoactive yellow protein, a bacterial light sensor, has been proposed as the PAS structural prototype yet contains an N-terminal helix-turn-helix motif not found in other PAS domains. Here we describe the atomic resolution structure of a photoactive yellow protein deletion mutant lacking this motif, revealing that the PAS domain is indeed able to fold independently and is not affected by the removal of these residues. Computer simulations of currently known PAS domain structures reveal that these domains are not only structurally conserved but are also similar in their conformational flexibilities. The observed motions point to a possible common mechanism for communicating ligand binding/activation to downstream transducer proteins.
-
{{STRUCTURE_1odv| PDB=1odv | SCENE= }}
+
PAS domains. Common structure and common flexibility.,Vreede J, van der Horst MA, Hellingwerf KJ, Crielaard W, van Aalten DM J Biol Chem. 2003 May 16;278(20):18434-9. Epub 2003 Mar 14. PMID:12639952<ref>PMID:12639952</ref>
-
===PHOTOACTIVE YELLOW PROTEIN 1-25 DELETION MUTANT===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_12639952}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[1odv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODV OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:012639952</ref><references group="xtra"/>
+
[[Category: Halorhodospira halophila]]
[[Category: Halorhodospira halophila]]
[[Category: Aalten, D M.F Van.]]
[[Category: Aalten, D M.F Van.]]

Revision as of 15:31, 28 September 2014

PHOTOACTIVE YELLOW PROTEIN 1-25 DELETION MUTANT

1odv, resolution 1.14Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1odv"
Views
Personal tools
Navigation
Toolbox