1fe6

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[[Image:1fe6.jpg|left|200px]]<br /><applet load="1fe6" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1fe6.jpg|left|200px]]
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caption="1fe6, resolution 1.80&Aring;" />
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'''CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER'''<br />
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{{Structure
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|PDB= 1fe6 |SIZE=350|CAPTION= <scene name='initialview01'>1fe6</scene>, resolution 1.80&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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}}
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'''CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1FE6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylothermus_marinus Staphylothermus marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FE6 OCA].
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1FE6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylothermus_marinus Staphylothermus marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FE6 OCA].
==Reference==
==Reference==
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Crystal structure of a naturally occurring parallel right-handed coiled coil tetramer., Stetefeld J, Jenny M, Schulthess T, Landwehr R, Engel J, Kammerer RA, Nat Struct Biol. 2000 Sep;7(9):772-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10966648 10966648]
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Crystal structure of a naturally occurring parallel right-handed coiled coil tetramer., Stetefeld J, Jenny M, Schulthess T, Landwehr R, Engel J, Kammerer RA, Nat Struct Biol. 2000 Sep;7(9):772-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10966648 10966648]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Staphylothermus marinus]]
[[Category: Staphylothermus marinus]]
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[[Category: right handed coiled coil]]
[[Category: right handed coiled coil]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:37:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:08:00 2008''

Revision as of 09:08, 20 March 2008

Image:1fe6.jpg


PDB ID 1fe6

Drag the structure with the mouse to rotate
, resolution 1.80Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER


Overview

The crystal structure of a polypeptide chain fragment from the surface layer protein tetrabrachion from Staphylothermus marinus has been determined at 1.8 A resolution. As proposed on the basis of the presence of 11-residue repeats, the polypeptide chain fragment forms a parallel right-handed coiled coil structure. Complementary hydrophobic interactions and complex networks of surface salt bridges result in an extremely thermostable tetrameric structure with remarkable properties. In marked contrast to left-handed coiled coil tetramers, the right-handed coiled coil reveals large hydrophobic cavities that are filled with water molecules. As a consequence, the packing of the hydrophobic core differs markedly from that of a right-handed parallel coiled coil tetramer that was designed on the basis of left-handed coiled coil structures.

About this Structure

1FE6 is a Single protein structure of sequence from Staphylothermus marinus. Full crystallographic information is available from OCA.

Reference

Crystal structure of a naturally occurring parallel right-handed coiled coil tetramer., Stetefeld J, Jenny M, Schulthess T, Landwehr R, Engel J, Kammerer RA, Nat Struct Biol. 2000 Sep;7(9):772-6. PMID:10966648

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