1p86

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1p86.png|left|200px]]
+
==Real space refined coordinates of the 50S subunit fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome==
 +
<StructureSection load='1p86' size='340' side='right' caption='[[1p86]], [[Resolution|resolution]] 11.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1p86]] is a 27 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P86 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P86 FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gix|1gix]], [[1giy|1giy]], [[1jj2|1jj2]], [[1ibl|1ibl]], [[1lnr|1lnr]], [[1m5g|1m5g]], [[1p87|1p87]]</td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p86 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p86 RCSB], [http://www.ebi.ac.uk/pdbsum/1p86 PDBsum]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/1p86_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Cryo-EM density maps showing the 70S ribosome of E. coli in two different functional states related by a ratchet-like motion were analyzed using real-space refinement. Comparison of the two resulting atomic models shows that the ribosome changes from a compact structure to a looser one, coupled with the rearrangement of many of the proteins. Furthermore, in contrast to the unchanged inter-subunit bridges formed wholly by RNA, the bridges involving proteins undergo large conformational changes following the ratchet-like motion, suggesting an important role of ribosomal proteins in facilitating the dynamics of translation.
-
{{STRUCTURE_1p86| PDB=1p86 | SCENE= }}
+
Study of the structural dynamics of the E coli 70S ribosome using real-space refinement.,Gao H, Sengupta J, Valle M, Korostelev A, Eswar N, Stagg SM, Van Roey P, Agrawal RK, Harvey SC, Sali A, Chapman MS, Frank J Cell. 2003 Jun 13;113(6):789-801. PMID:12809609<ref>PMID:12809609</ref>
-
===Real space refined coordinates of the 50S subunit fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_12809609}}
+
-
 
+
-
==About this Structure==
+
-
[[1p86]] is a 27 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P86 OCA].
+
==See Also==
==See Also==
-
*[[Ribosomal protein L11|Ribosomal protein L11]]
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
-
*[[Ribosomal protein L13|Ribosomal protein L13]]
+
== References ==
-
*[[Ribosomal protein L14|Ribosomal protein L14]]
+
<references/>
-
*[[Ribosomal protein L15|Ribosomal protein L15]]
+
__TOC__
-
*[[Ribosomal protein L16|Ribosomal protein L16]]
+
</StructureSection>
-
*[[Ribosomal protein L17|Ribosomal protein L17]]
+
-
*[[Ribosomal protein L18|Ribosomal protein L18]]
+
-
*[[Ribosomal protein L19|Ribosomal protein L19]]
+
-
*[[Ribosomal protein L2|Ribosomal protein L2]]
+
-
*[[Ribosomal protein L20|Ribosomal protein L20]]
+
-
*[[Ribosomal protein L21|Ribosomal protein L21]]
+
-
*[[Ribosomal protein L22|Ribosomal protein L22]]
+
-
*[[Ribosomal protein L23|Ribosomal protein L23]]
+
-
*[[Ribosomal protein L24|Ribosomal protein L24]]
+
-
*[[Ribosomal protein L25|Ribosomal protein L25]]
+
-
*[[Ribosomal protein L27|Ribosomal protein L27]]
+
-
*[[Ribosomal protein L29|Ribosomal protein L29]]
+
-
*[[Ribosomal protein L3|Ribosomal protein L3]]
+
-
*[[Ribosomal protein L30|Ribosomal protein L30]]
+
-
*[[Ribosomal protein L32|Ribosomal protein L32]]
+
-
*[[Ribosomal protein L33|Ribosomal protein L33]]
+
-
*[[Ribosomal protein L36|Ribosomal protein L36]]
+
-
*[[Ribosomal protein L4|Ribosomal protein L4]]
+
-
*[[Ribosomal protein L5|Ribosomal protein L5]]
+
-
*[[Ribosomal protein L6|Ribosomal protein L6]]
+
-
*[[Ribosomal protein L9|Ribosomal protein L9]]
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:012809609</ref><references group="xtra"/>
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Agrawal, R K.]]
[[Category: Agrawal, R K.]]

Revision as of 21:03, 28 September 2014

Real space refined coordinates of the 50S subunit fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome

1p86, resolution 11.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1p86"
Views
Personal tools
Navigation
Toolbox