1ftn

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[[Image:1ftn.jpg|left|200px]]<br /><applet load="1ftn" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1ftn.jpg|left|200px]]
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caption="1ftn, resolution 2.1&Aring;" />
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'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''<br />
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{{Structure
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|PDB= 1ftn |SIZE=350|CAPTION= <scene name='initialview01'>1ftn</scene>, resolution 2.1&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene>
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|ACTIVITY=
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|GENE= SYNTHETIC HUMAN RHOA GENE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1FTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GDP:'>GDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FTN OCA].
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1FTN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FTN OCA].
==Reference==
==Reference==
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Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9302995 9302995]
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Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9302995 9302995]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: small p-protein]]
[[Category: small p-protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:42:31 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:13:51 2008''

Revision as of 09:13, 20 March 2008

Image:1ftn.jpg


PDB ID 1ftn

Drag the structure with the mouse to rotate
, resolution 2.1Å
Ligands: and
Gene: SYNTHETIC HUMAN RHOA GENE (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX


Overview

RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.

About this Structure

1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995

Page seeded by OCA on Thu Mar 20 11:13:51 2008

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