2f8a
From Proteopedia
(Difference between revisions)
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- | + | ==Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1== | |
- | + | <StructureSection load='2f8a' size='340' side='right' caption='[[2f8a]], [[Resolution|resolution]] 1.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2f8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F8A FirstGlance]. <br> | |
- | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene><br> | |
- | + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
- | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] </span></td></tr> | |
- | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f8a RCSB], [http://www.ebi.ac.uk/pdbsum/2f8a PDBsum]</span></td></tr> | |
- | == | + | <table> |
- | [[2f8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA]. | + | == Evolutionary Conservation == |
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/2f8a_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Glutathione peroxidase|Glutathione peroxidase]] | *[[Glutathione peroxidase|Glutathione peroxidase]] | ||
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
[[Category: Glutathione peroxidase]] | [[Category: Glutathione peroxidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] |
Revision as of 02:59, 29 September 2014
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
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Categories: Glutathione peroxidase | Homo sapiens | Delft, F von. | Edwards, A. | Gileadi, O. | Johansson, C. | Kavanagh, K L. | Oppermann, U. | SGC, Structural Genomics Consortium. | Smee, C. | Sundstrom, M. | Weigelt, J. | Oxidoreductase | Sgc | Structural genomic | Structural genomics consortium | Thioredoxin fold