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2g99

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[[Image:2g99.png|left|200px]]
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==Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5==
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<StructureSection load='2g99' size='340' side='right' caption='[[2g99]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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{{STRUCTURE_2g99| PDB=2g99 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2g99]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G99 FirstGlance]. <br>
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===Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5===
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2g9a|2g9a]]</td></tr>
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{{ABSTRACT_PUBMED_016600877}}
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g99 RCSB], [http://www.ebi.ac.uk/pdbsum/2g99 PDBsum]</span></td></tr>
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<table>
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==About this Structure==
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== Evolutionary Conservation ==
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[[2g99]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G99 OCA].
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/2g99_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Histone|Histone]]
*[[Histone|Histone]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016600877</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chai, J.]]
[[Category: Chai, J.]]

Revision as of 03:19, 29 September 2014

Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5

2g99, resolution 1.90Å

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