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3eaz

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[[Image:3eaz.png|left|200px]]
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==Crystal structure of SH2 domain of Human Csk (carboxyl-terminal src kinase), C122S mutant.==
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<StructureSection load='3eaz' size='340' side='right' caption='[[3eaz]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
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{{STRUCTURE_3eaz| PDB=3eaz | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3eaz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EAZ FirstGlance]. <br>
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===Crystal structure of SH2 domain of Human Csk (carboxyl-terminal src kinase), C122S mutant.===
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eac|3eac]], [[1k9a|1k9a]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
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==About this Structure==
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eaz RCSB], [http://www.ebi.ac.uk/pdbsum/3eaz PDBsum]</span></td></tr>
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[[3eaz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EAZ OCA].
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/3eaz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[C-Src tyrosine kinase|C-Src tyrosine kinase]]
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*[[Tyrosine kinase|Tyrosine kinase]]
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*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]

Revision as of 12:34, 29 September 2014

Crystal structure of SH2 domain of Human Csk (carboxyl-terminal src kinase), C122S mutant.

3eaz, resolution 1.31Å

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