1gqu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1gqu.gif|left|200px]]<br /><applet load="1gqu" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1gqu.gif|left|200px]]
-
caption="1gqu, resolution 2.5&Aring;" />
+
 
-
'''CRYSTAL STRUCTURE OF AN ALTERNATING A-T OLIGONUCLEOTIDE FRAGMENT WITH HOOGSTEEN BASE PAIRING'''<br />
+
{{Structure
 +
|PDB= 1gqu |SIZE=350|CAPTION= <scene name='initialview01'>1gqu</scene>, resolution 2.5&Aring;
 +
|SITE=
 +
|LIGAND=
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''CRYSTAL STRUCTURE OF AN ALTERNATING A-T OLIGONUCLEOTIDE FRAGMENT WITH HOOGSTEEN BASE PAIRING'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1GQU is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQU OCA].
+
1GQU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQU OCA].
==Reference==
==Reference==
-
Crystal structure of an antiparallel DNA fragment with Hoogsteen base pairing., Abrescia NG, Thompson A, Huynh-Dinh T, Subirana JA, Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2806-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11880632 11880632]
+
Crystal structure of an antiparallel DNA fragment with Hoogsteen base pairing., Abrescia NG, Thompson A, Huynh-Dinh T, Subirana JA, Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2806-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11880632 11880632]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Abrescia, N G.A.]]
[[Category: Abrescia, N G.A.]]
Line 19: Line 28:
[[Category: new dna structure]]
[[Category: new dna structure]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:53:01 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:26:46 2008''

Revision as of 09:26, 20 March 2008

Image:1gqu.gif


PDB ID 1gqu

Drag the structure with the mouse to rotate
, resolution 2.5Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF AN ALTERNATING A-T OLIGONUCLEOTIDE FRAGMENT WITH HOOGSTEEN BASE PAIRING


Overview

We report here an alternative double-helical structure of the DNA molecule. It has been found in the d(ATA(Br)UAT) and d(ATATAT) sequences by single-crystal x-ray crystallography. This sequence is found not only in TATA boxes, but also in other regulatory regions of DNA. Bases of the two antiparallel strands form Hoogsteen pairs, with adenines in the syn conformation. The structure is related neither to those found in triple helices nor to parallel DNA duplexes. Its conformational parameters are very similar to those of duplex DNA in the B form. Both forms may coexist under physiological conditions, although the Hoogsteen pairing greatly influences the recognition sites on DNA. Our results demonstrate that an alternative to the classical B-DNA double helix is possible.

About this Structure

1GQU is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure of an antiparallel DNA fragment with Hoogsteen base pairing., Abrescia NG, Thompson A, Huynh-Dinh T, Subirana JA, Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2806-11. PMID:11880632

Page seeded by OCA on Thu Mar 20 11:26:46 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gqu"
Personal tools