3gv4
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG== | |
| - | + | <StructureSection load='3gv4' size='340' side='right' caption='[[3gv4]], [[Resolution|resolution]] 1.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3gv4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GV4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GV4 FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDAC6, KIAA0901, JM21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr> | |
| - | == | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gv4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gv4 RCSB], [http://www.ebi.ac.uk/pdbsum/3gv4 PDBsum]</span></td></tr> |
| - | [[3gv4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GV4 OCA]. | + | <table> |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/3gv4_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Histone deacetylase|Histone deacetylase]] | *[[Histone deacetylase|Histone deacetylase]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Histone deacetylase]] | [[Category: Histone deacetylase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 13:32, 29 September 2014
Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG
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Categories: Histone deacetylase | Homo sapiens | Arrowsmith, C H. | Bochkarev, A. | Bountra, C. | Dhe-Paganon, S. | Dong, A. | Edwards, A M. | Kozieradzki, I. | Li, Y. | Loppnau, P. | MacKenzie, F. | Min, J. | Ouyang, H. | Ravichandran, M. | SGC, Structural Genomics Consortium. | Weigelt, J. | Actin-binding | Chromatin regulator | Hdac6 | Hydrolase | Metal-binding | Nucleus | Phosphoprotein | Repressor | Sgc | Structural genomic | Structural genomics consortium | Transcription | Transcription regulation | Ubiquitin c-terminal peptide rlrgg | Zinc finger | Zinc-finger
