1s7o

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[[Image:1s7o.png|left|200px]]
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==Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes==
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<StructureSection load='1s7o' size='340' side='right' caption='[[1s7o]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1s7o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_m3 Streptococcus pyogenes serotype m3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S7O FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPY1201, SPYM3_0842, SPS1042, SPYM18_1152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=301448 Streptococcus pyogenes serotype M3])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s7o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s7o RCSB], [http://www.ebi.ac.uk/pdbsum/1s7o PDBsum], [http://www.topsan.org/Proteins/BSGC/1s7o TOPSAN]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s7/1s7o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of the putative DNA-binding protein SP_1288 (gi/15675166, also listed as gi/28895954) from Streptococcus pyogenes has been determined by X-ray crystallography to a resolution of 2.3 A using anomalous diffraction data at the Se peak wavelength. SP_1288 belongs to a family of proteins whose cellular function is associated with the signal recognition particle; no structural information has been available until now about the members of the family. Crystallographic analysis revealed that the overall fold of SP_1288 consists exclusively of alpha-helices and that 75% of the structure has good similarity to domain 4 of the sigma subunit of RNA polymerase. This suggests its possible involvement in the biochemical function of transcription initiation, which includes interaction with DNA.
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{{STRUCTURE_1s7o| PDB=1s7o | SCENE= }}
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Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes.,Oganesyan V, Pufan R, DeGiovanni A, Yokota H, Kim R, Kim SH Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1266-71. Epub 2004, Jun 22. PMID:15213388<ref>PMID:15213388</ref>
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===Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15213388}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1s7o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_m3 Streptococcus pyogenes serotype m3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7O OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015213388</ref><references group="xtra"/>
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[[Category: Streptococcus pyogenes serotype m3]]
[[Category: Streptococcus pyogenes serotype m3]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]

Revision as of 15:09, 29 September 2014

Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes

1s7o, resolution 2.31Å

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