1h1k

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[[Image:1h1k.gif|left|200px]]<br /><applet load="1h1k" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1h1k.gif|left|200px]]
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caption="1h1k, resolution 10.&Aring;" />
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'''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA'''<br />
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{{Structure
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|PDB= 1h1k |SIZE=350|CAPTION= <scene name='initialview01'>1h1k</scene>, resolution 10.&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1H1K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1K OCA].
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1H1K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1K OCA].
==Reference==
==Reference==
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The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12186935 12186935]
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The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12186935 12186935]
[[Category: Bluetongue virus]]
[[Category: Bluetongue virus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: virus]]
[[Category: virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:56:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:30:56 2008''

Revision as of 09:30, 20 March 2008


PDB ID 1h1k

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, resolution 10.Å
Coordinates: save as pdb, mmCIF, xml



THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA


Overview

Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.

About this Structure

1H1K is a Single protein structure of sequence from Bluetongue virus. Full crystallographic information is available from OCA.

Reference

The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:12186935

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