1h1k
From Proteopedia
Line 1: | Line 1: | ||
- | [[Image:1h1k.gif|left|200px]] | + | [[Image:1h1k.gif|left|200px]] |
- | + | ||
- | '''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA''' | + | {{Structure |
+ | |PDB= 1h1k |SIZE=350|CAPTION= <scene name='initialview01'>1h1k</scene>, resolution 10.Å | ||
+ | |SITE= | ||
+ | |LIGAND= | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA''' | ||
+ | |||
==Overview== | ==Overview== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
- | 1H1K is a [ | + | 1H1K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1K OCA]. |
==Reference== | ==Reference== | ||
- | The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:[http:// | + | The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12186935 12186935] |
[[Category: Bluetongue virus]] | [[Category: Bluetongue virus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
Line 25: | Line 34: | ||
[[Category: virus]] | [[Category: virus]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:30:56 2008'' |
Revision as of 09:30, 20 March 2008
| |||||||
, resolution 10.Å | |||||||
---|---|---|---|---|---|---|---|
Coordinates: | save as pdb, mmCIF, xml |
THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Overview
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
About this Structure
1H1K is a Single protein structure of sequence from Bluetongue virus. Full crystallographic information is available from OCA.
Reference
The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:12186935
Page seeded by OCA on Thu Mar 20 11:30:56 2008