1h21

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1h21.jpg|left|200px]]<br /><applet load="1h21" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1h21.jpg|left|200px]]
-
caption="1h21, resolution 2.50&Aring;" />
+
 
-
'''A NOVEL IRON CENTRE IN THE SPLIT-SORET CYTOCHROME C FROM DESULFOVIBRIO DESULFURICANS ATCC 27774'''<br />
+
{{Structure
 +
|PDB= 1h21 |SIZE=350|CAPTION= <scene name='initialview01'>1h21</scene>, resolution 2.50&Aring;
 +
|SITE= <scene name='pdbsite=AC1:Hec+Binding+Site+For+Chain+D'>AC1</scene>
 +
|LIGAND= <scene name='pdbligand=HEC:HEME C'>HEC</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''A NOVEL IRON CENTRE IN THE SPLIT-SORET CYTOCHROME C FROM DESULFOVIBRIO DESULFURICANS ATCC 27774'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1H21 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans] with <scene name='pdbligand=HEC:'>HEC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1DDC. Known structural/functional Site: <scene name='pdbsite=AC1:Hec+Binding+Site+For+Chain+D'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H21 OCA].
+
1H21 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]. This structure supersedes the now removed PDB entry 1DDC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H21 OCA].
==Reference==
==Reference==
-
A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774., Abreu IA, Lourenco AI, Xavier AV, LeGall J, Coelho AV, Matias PM, Pinto DM, Armenia Carrondo M, Teixeira M, Saraiva LM, J Biol Inorg Chem. 2003 Feb;8(3):360-70. Epub 2002 Dec 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12589573 12589573]
+
A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774., Abreu IA, Lourenco AI, Xavier AV, LeGall J, Coelho AV, Matias PM, Pinto DM, Armenia Carrondo M, Teixeira M, Saraiva LM, J Biol Inorg Chem. 2003 Feb;8(3):360-70. Epub 2002 Dec 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12589573 12589573]
[[Category: Desulfovibrio desulfuricans]]
[[Category: Desulfovibrio desulfuricans]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 31: Line 40:
[[Category: sulfate respiration]]
[[Category: sulfate respiration]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:56:29 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:31:05 2008''

Revision as of 09:31, 20 March 2008

Image:1h21.jpg


PDB ID 1h21

Drag the structure with the mouse to rotate
, resolution 2.50Å
Sites:
Ligands:
Coordinates: save as pdb, mmCIF, xml



A NOVEL IRON CENTRE IN THE SPLIT-SORET CYTOCHROME C FROM DESULFOVIBRIO DESULFURICANS ATCC 27774


Overview

The facultative sulfate/nitrate-reducing bacterium Desulfovibrio desulfuricans ATCC 27774 harbours a split-Soret cytochrome c. This cytochrome is a homodimeric protein, having two bis-histidinyl c-type haems per monomer. It has an unique architecture at the haem domain: each haem has one of the coordinating histidines provided by the other monomer, and in each monomer the haems are parallel to each other, almost in van der Waals contact. This work reports the cloning and sequencing of the gene encoding for this cytochrome and shows, by transcriptional analysis, that it is more expressed in nitrate-grown cells than in sulfate-grown ones. In addition, the gene-deduced amino acid sequence revealed two new cysteine residues that could be involved in the binding of a non-haem iron centre. Indeed, the presence of a novel type of an iron-sulfur centre (possibly of the [2Fe-2S] type) was demonstrated by EPR spectroscopy, and putative models for its localization and structure in the cytochrome molecule are proposed on the basis of the so-far-known 3D crystallographic structure of the aerobically purified split-Soret cytochrome, which lacks this centre.

About this Structure

1H21 is a Single protein structure of sequence from Desulfovibrio desulfuricans. This structure supersedes the now removed PDB entry 1DDC. Full crystallographic information is available from OCA.

Reference

A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774., Abreu IA, Lourenco AI, Xavier AV, LeGall J, Coelho AV, Matias PM, Pinto DM, Armenia Carrondo M, Teixeira M, Saraiva LM, J Biol Inorg Chem. 2003 Feb;8(3):360-70. Epub 2002 Dec 19. PMID:12589573

Page seeded by OCA on Thu Mar 20 11:31:05 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h21"
Personal tools