1wcx
From Proteopedia
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- | + | ==Crystal Structure of Mutant Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (L75M/I193M/L248M, SeMet derivative, Form-1 crystal)== | |
- | + | <StructureSection load='1wcx' size='340' side='right' caption='[[1wcx]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1wcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WCX FirstGlance]. <br> | |
- | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br> | |
- | + | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
- | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wcw|1wcw]]</td></tr> | |
- | == | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uroporphyrinogen-III_synthase Uroporphyrinogen-III synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.75 4.2.1.75] </span></td></tr> |
- | [[1wcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCX OCA]. | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wcx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wcx RCSB], [http://www.ebi.ac.uk/pdbsum/1wcx PDBsum], [http://www.topsan.org/Proteins/RSGI/1wcx TOPSAN]</span></td></tr> |
+ | <table> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/1wcx_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Uroporphyrinogen-III synthase]] | [[Category: Uroporphyrinogen-III synthase]] |
Revision as of 19:00, 29 September 2014
Crystal Structure of Mutant Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (L75M/I193M/L248M, SeMet derivative, Form-1 crystal)
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Categories: Thermus thermophilus | Uroporphyrinogen-III synthase | Kuramitsu, S. | Matsuura, T. | Mizohata, E. | Murayama, K. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Sakai, H. | Shirouzu, M. | Terada, T. | Yokoyama, S. | Congenital erythropoietic porphyria | Lyase | Porphyrin | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic | Uroporphyrinogen