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1hf9

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[[Image:1hf9.jpg|left|200px]]<br /><applet load="1hf9" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1hf9.jpg|left|200px]]
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caption="1hf9" />
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'''C-TERMINAL COILED-COIL DOMAIN FROM BOVINE IF1'''<br />
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{{Structure
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|PDB= 1hf9 |SIZE=350|CAPTION= <scene name='initialview01'>1hf9</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY=
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}}
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'''C-TERMINAL COILED-COIL DOMAIN FROM BOVINE IF1'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1HF9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HF9 OCA].
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1HF9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HF9 OCA].
==Reference==
==Reference==
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Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase., Gordon-Smith DJ, Carbajo RJ, Yang JC, Videler H, Runswick MJ, Walker JE, Neuhaus D, J Mol Biol. 2001 Apr 27;308(2):325-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11327770 11327770]
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Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase., Gordon-Smith DJ, Carbajo RJ, Yang JC, Videler H, Runswick MJ, Walker JE, Neuhaus D, J Mol Biol. 2001 Apr 27;308(2):325-39. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11327770 11327770]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transit peptide]]
[[Category: transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:00:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:36:31 2008''

Revision as of 09:36, 20 March 2008


PDB ID 1hf9

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C-TERMINAL COILED-COIL DOMAIN FROM BOVINE IF1


Overview

Bovine IF(1) is a basic, 84 amino acid residue protein that inhibits the hydrolytic action of the F(1)F(0) ATP synthase in mitochondria under anaerobic conditions. Its oligomerization state is dependent on pH. At a pH value below 6.5 it forms an active dimer. At higher pH values, two dimers associate to form an inactive tetramer. Here, we present the solution structure of a C-terminal fragment of IF(1) (44-84) containing all five of the histidine residues present in the sequence. Most unusually, the molecule forms an anti-parallel coiled-coil in which three of the five histidine residues occupy key positions at the dimer interface.

About this Structure

1HF9 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase., Gordon-Smith DJ, Carbajo RJ, Yang JC, Videler H, Runswick MJ, Walker JE, Neuhaus D, J Mol Biol. 2001 Apr 27;308(2):325-39. PMID:11327770

Page seeded by OCA on Thu Mar 20 11:36:31 2008

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