1ufn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1ufn" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:1ufn.png|left|200px]]
+
==Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)==
-
 
+
<StructureSection load='1ufn' size='340' side='right' caption='[[1ufn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-
{{STRUCTURE_1ufn| PDB=1ufn | SCENE= }}
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1ufn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UFN FirstGlance]. <br>
-
===Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)===
+
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 5830484A20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-
 
+
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ufn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ufn RCSB], [http://www.ebi.ac.uk/pdbsum/1ufn PDBsum], [http://www.topsan.org/Proteins/RSGI/1ufn TOPSAN]</span></td></tr>
-
 
+
<table>
-
==About this Structure==
+
== Disease ==
-
[[1ufn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA].
+
[[http://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis.<ref>PMID:15815631</ref>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells.<ref>PMID:15815631</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufn_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Aoki, M.]]
[[Category: Aoki, M.]]

Revision as of 21:09, 29 September 2014

Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ufn"
Views
Personal tools
Navigation
Toolbox