1huu
From Proteopedia
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- | [[Image:1huu.jpg|left|200px]] | + | [[Image:1huu.jpg|left|200px]] |
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- | '''DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS''' | + | {{Structure |
+ | |PDB= 1huu |SIZE=350|CAPTION= <scene name='initialview01'>1huu</scene>, resolution 2.0Å | ||
+ | |SITE= | ||
+ | |LIGAND= | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS''' | ||
+ | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1HUU is a [ | + | 1HUU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HUU OCA]. |
==Reference== | ==Reference== | ||
- | A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:[http:// | + | A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2508086 2508086] |
[[Category: Geobacillus stearothermophilus]] | [[Category: Geobacillus stearothermophilus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: minor groove binder]] | [[Category: minor groove binder]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:41:53 2008'' |
Revision as of 09:41, 20 March 2008
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, resolution 2.0Å | |||||||
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Coordinates: | save as pdb, mmCIF, xml |
DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS
Overview
The prokaryotic protein HU, integration host factor (IHF) from Escherichia coli, and transcription factor 1 (TF1) from bacteriophage SPO1 are closely related molecules. Biochemical results suggest that the role of these proteins is to bind and bend DNA. From the high-resolution structure of HU, we propose a model for this interaction with DNA. Crucial amino acid differences between the proteins can be rationalized in terms of their different specific functions.
About this Structure
1HUU is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.
Reference
A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:2508086
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