1huu
From Proteopedia
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| - | [[Image:1huu.jpg|left|200px]]  | + | [[Image:1huu.jpg|left|200px]]  | 
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| - | '''DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS'''  | + |  {{Structure  | 
| + | |PDB= 1huu |SIZE=350|CAPTION= <scene name='initialview01'>1huu</scene>, resolution 2.0Å  | ||
| + | |SITE=   | ||
| + | |LIGAND=   | ||
| + | |ACTIVITY=   | ||
| + | |GENE=   | ||
| + | }}  | ||
| + | |||
| + | '''DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS'''  | ||
| + | |||
==Overview==  | ==Overview==  | ||
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==About this Structure==  | ==About this Structure==  | ||
| - | 1HUU is a [  | + | 1HUU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HUU OCA].   | 
==Reference==  | ==Reference==  | ||
| - | A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:[http://  | + | A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2508086 2508086]  | 
[[Category: Geobacillus stearothermophilus]]  | [[Category: Geobacillus stearothermophilus]]  | ||
[[Category: Single protein]]  | [[Category: Single protein]]  | ||
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[[Category: minor groove binder]]  | [[Category: minor groove binder]]  | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu   | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:41:53 2008''  | 
Revision as of 09:41, 20 March 2008
 
 
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS
Overview
The prokaryotic protein HU, integration host factor (IHF) from Escherichia coli, and transcription factor 1 (TF1) from bacteriophage SPO1 are closely related molecules. Biochemical results suggest that the role of these proteins is to bind and bend DNA. From the high-resolution structure of HU, we propose a model for this interaction with DNA. Crucial amino acid differences between the proteins can be rationalized in terms of their different specific functions.
About this Structure
1HUU is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.
Reference
A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:2508086
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