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2qmp

From Proteopedia

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[[Image:2qmp.png|left|200px]]
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==Crystal Structure of HIV-1 protease complexed with PL-100==
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<StructureSection load='2qmp' size='340' side='right' caption='[[2qmp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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{{STRUCTURE_2qmp| PDB=2qmp | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2qmp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QMP FirstGlance]. <br>
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===Crystal Structure of HIV-1 protease complexed with PL-100===
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A00:N-[(5S)-5-{[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO}-6-HYDROXYHEXYL]-NALPHA-(METHOXYCARBONYL)-BETA-PHENYL-L-PHENYLALANINAMIDE'>A00</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qmp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qmp RCSB], [http://www.ebi.ac.uk/pdbsum/2qmp PDBsum]</span></td></tr>
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==About this Structure==
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<table>
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[[2qmp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QMP OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qm/2qmp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]

Revision as of 18:55, 30 September 2014

Crystal Structure of HIV-1 protease complexed with PL-100

2qmp, resolution 1.80Å

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