2wns

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{{STRUCTURE_2wns| PDB=2wns | SCENE= }}
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==HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)==
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===HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)===
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<StructureSection load='2wns' size='340' side='right' caption='[[2wns]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNS FirstGlance]. <br>
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[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA].
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OMP:OROTIDINE-5-MONOPHOSPHATE'>OMP</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgy|2jgy]], [[2v30|2v30]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wns OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wns RCSB], [http://www.ebi.ac.uk/pdbsum/2wns PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wns_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]

Revision as of 01:12, 1 October 2014

HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)

2wns, resolution 1.90Å

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OCA

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