2uy1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2uy1" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:2uy1.png|left|200px]]
+
==CRYSTAL STRUCTURE OF CSTF-77==
 +
<StructureSection load='2uy1' size='340' side='right' caption='[[2uy1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2uy1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UY1 FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uy1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uy1 RCSB], [http://www.ebi.ac.uk/pdbsum/2uy1 PDBsum]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uy1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The cleavage stimulation factor (CstF) is essential for the first step of poly(A) tail formation at the 3' ends of mRNAs. This heterotrimeric complex is built around the 77-kDa protein bridging both CstF-64 and CstF-50 subunits. We have solved the crystal structure of the 77-kDa protein from Encephalitozoon cuniculi at a resolution of 2 A. The structure folds around 11 Half-a-TPR repeats defining two domains. The crystal structure reveals a tight homodimer exposing phylogenetically conserved areas for interaction with protein partners. Mapping experiments identify the C-terminal region of Rna14p, the yeast counterpart of CstF-77, as the docking domain for Rna15p, the yeast CstF-64 homologue.
-
{{STRUCTURE_2uy1| PDB=2uy1 | SCENE= }}
+
The structure of the CstF-77 homodimer provides insights into CstF assembly.,Legrand P, Pinaud N, Minvielle-Sebastia L, Fribourg S Nucleic Acids Res. 2007;35(13):4515-22. Epub 2007 Jun 21. PMID:17584787<ref>PMID:17584787</ref>
-
===CRYSTAL STRUCTURE OF CSTF-77===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_17584787}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[2uy1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UY1 OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:017584787</ref><references group="xtra"/>
+
[[Category: Encephalitozoon cuniculi]]
[[Category: Encephalitozoon cuniculi]]
[[Category: Fribourg, S.]]
[[Category: Fribourg, S.]]

Revision as of 01:35, 1 October 2014

CRYSTAL STRUCTURE OF CSTF-77

2uy1, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2uy1"
Views
Personal tools
Navigation
Toolbox