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2vsn
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==STRUCTURE AND TOPOLOGICAL ARRANGEMENT OF AN O-GLCNAC TRANSFERASE HOMOLOG: INSIGHT INTO MOLECULAR CONTROL OF INTRACELLULAR GLYCOSYLATION== |
| + | <StructureSection load='2vsn' size='340' side='right' caption='[[2vsn]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2vsn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris Xanthomonas campestris pv. campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VSN FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vsn RCSB], [http://www.ebi.ac.uk/pdbsum/2vsn PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vsn_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | N-Acetylglucosamine (O-GlcNAc) modification of proteins provides a mechanism for the control of diverse cellular processes through a dynamic interplay with phosphorylation. UDP-GlcNAc:polypeptidyl transferase (OGT) catalyzes O-GlcNAc addition. The structure of an intact OGT homolog and kinetic analysis of human OGT variants reveal a contiguous superhelical groove that directs substrates to the active site. | ||
| - | + | Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation.,Martinez-Fleites C, Macauley MS, He Y, Shen DL, Vocadlo DJ, Davies GJ Nat Struct Mol Biol. 2008 Jul;15(7):764-5. Epub 2008 Jun 8. PMID:18536723<ref>PMID:18536723</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | == | + | |
| - | < | + | |
[[Category: Xanthomonas campestris pv. campestris]] | [[Category: Xanthomonas campestris pv. campestris]] | ||
[[Category: Davies, G J.]] | [[Category: Davies, G J.]] | ||
Revision as of 01:50, 1 October 2014
STRUCTURE AND TOPOLOGICAL ARRANGEMENT OF AN O-GLCNAC TRANSFERASE HOMOLOG: INSIGHT INTO MOLECULAR CONTROL OF INTRACELLULAR GLYCOSYLATION
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