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2w0w

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[[Image:2w0w.png|left|200px]]
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==CRYSTAL STRUCTURE OF GLMU FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH QUINAZOLINE INHIBITOR 2==
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<StructureSection load='2w0w' size='340' side='right' caption='[[2w0w]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
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{{STRUCTURE_2w0w| PDB=2w0w | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2w0w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0W FirstGlance]. <br>
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===CRYSTAL STRUCTURE OF GLMU FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH QUINAZOLINE INHIBITOR 2===
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LZS:N-{6-(CYCLOPROPYLMETHOXY)-7-METHOXY-2-[6-(2-METHYLPROPYL)-5-OXO-3,4,5,6-TETRAHYDRO-2,6-NAPHTHYRIDIN-2(1H)-YL]QUINAZOLIN-4-YL}-2,2,2-TRIFLUOROETHANESULFONAMIDE'>LZS</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2v0h|2v0h]], [[2v0l|2v0l]], [[2w0v|2w0v]], [[2v0j|2v0j]], [[2vd4|2vd4]], [[2v0k|2v0k]], [[2v0i|2v0i]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosamine-1-phosphate_N-acetyltransferase Glucosamine-1-phosphate N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.157 2.3.1.157] </span></td></tr>
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==About this Structure==
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0w RCSB], [http://www.ebi.ac.uk/pdbsum/2w0w PDBsum]</span></td></tr>
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[[2w0w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0W OCA].
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w0/2w0w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Glucosamine-1-phosphate N-acetyltransferase]]
[[Category: Glucosamine-1-phosphate N-acetyltransferase]]
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]

Revision as of 02:08, 1 October 2014

CRYSTAL STRUCTURE OF GLMU FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH QUINAZOLINE INHIBITOR 2

2w0w, resolution 2.59Å

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