2yqk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_2yqk| PDB=2yqk | SCENE= }}
+
==Solution structure of the SANT domain in Arginine-glutamic acid dipeptide (RE) repeats==
-
===Solution structure of the SANT domain in Arginine-glutamic acid dipeptide (RE) repeats===
+
<StructureSection load='2yqk' size='340' side='right' caption='[[2yqk]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-
 
+
== Structural highlights ==
-
==Disease==
+
<table><tr><td colspan='2'>[[2yqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQK FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RERE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yqk RCSB], [http://www.ebi.ac.uk/pdbsum/2yqk PDBsum], [http://www.topsan.org/Proteins/RSGI/2yqk TOPSAN]</span></td></tr>
 +
<table>
 +
== Disease ==
[[http://www.uniprot.org/uniprot/RERE_HUMAN RERE_HUMAN]] Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).
[[http://www.uniprot.org/uniprot/RERE_HUMAN RERE_HUMAN]] Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).
-
 
+
== Function ==
-
==Function==
+
[[http://www.uniprot.org/uniprot/RERE_HUMAN RERE_HUMAN]] Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.<ref>PMID:11331249</ref>
-
[[http://www.uniprot.org/uniprot/RERE_HUMAN RERE_HUMAN]] Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.<ref>PMID:11331249</ref>
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
[[2yqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQK OCA].
+
<jmolCheckbox>
-
 
+
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yq/2yqk_consurf.spt"</scriptWhenChecked>
-
==Reference==
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
<references group="xtra"/><references/>
+
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: He, F.]]
[[Category: He, F.]]

Revision as of 05:40, 2 October 2014

Solution structure of the SANT domain in Arginine-glutamic acid dipeptide (RE) repeats

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2yqk"
Views
Personal tools
Navigation
Toolbox