1m5a

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{{STRUCTURE_1m5a| PDB=1m5a | SCENE= }}
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==Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution==
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===Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution===
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<StructureSection load='1m5a' size='340' side='right' caption='[[1m5a]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[1m5a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M5A FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/INS_PIG INS_PIG]] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene><br>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m5a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m5a RCSB], [http://www.ebi.ac.uk/pdbsum/1m5a PDBsum]</span></td></tr>
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==About this Structure==
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<table>
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[[1m5a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M5A OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m5/1m5a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]
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__TOC__
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</StructureSection>
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Korber, F C.]]
[[Category: Korber, F C.]]

Revision as of 05:35, 3 October 2014

Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution

1m5a, resolution 1.20Å

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