This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1j59
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1j59.gif|left|200px]] | + | [[Image:1j59.gif|left|200px]] |
| - | + | ||
| - | '''CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE''' | + | {{Structure |
| + | |PDB= 1j59 |SIZE=350|CAPTION= <scene name='initialview01'>1j59</scene>, resolution 2.50Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=CMP:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE'>CMP</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1J59 is a [ | + | 1J59 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry 1BER. The following page contains interesting information on the relation of 1J59 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb48_1.html Catabolite Activator Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J59 OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface., Parkinson G, Wilson C, Gunasekera A, Ebright YW, Ebright RE, Berman HM, J Mol Biol. 1996 Jul 19;260(3):395-408. PMID:[http:// | + | Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface., Parkinson G, Wilson C, Gunasekera A, Ebright YW, Ebright RE, Berman HM, J Mol Biol. 1996 Jul 19;260(3):395-408. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8757802 8757802] |
[[Category: Catabolite Activator Protein]] | [[Category: Catabolite Activator Protein]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| Line 24: | Line 33: | ||
[[Category: protein-dna complex]] | [[Category: protein-dna complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:59:06 2008'' |
Revision as of 09:59, 20 March 2008
| |||||||
| , resolution 2.50Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Overview
The crystallographic structure of the CAP-DNA complex at 3.0 A resolution has been reported previously. For technical reasons, the reported structure had been determined using a gapped DNA molecule lacking two phosphates important for CAP-DNA interaction. In this work, we report the crystallographic structure of the CAP-DNA complex at 2.5 A resolution using a DNA molecule having all phosphates important for CAP-DNA interaction. The present resolution permits unambiguous identification of amino acid-base and amino acid-phosphate hydrogen bonded contacts in the CAP-DNA complex. In addition, the present resolution permits accurate definition of the kinked DNA conformation in the CAP-DNA complex.
About this Structure
1J59 is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1BER. The following page contains interesting information on the relation of 1J59 with [Catabolite Activator Protein]. Full crystallographic information is available from OCA.
Reference
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface., Parkinson G, Wilson C, Gunasekera A, Ebright YW, Ebright RE, Berman HM, J Mol Biol. 1996 Jul 19;260(3):395-408. PMID:8757802
Page seeded by OCA on Thu Mar 20 11:59:06 2008
