1j6z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1j6z.gif|left|200px]]<br /><applet load="1j6z" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1j6z.gif|left|200px]]
-
caption="1j6z, resolution 1.54&Aring;" />
+
 
-
'''UNCOMPLEXED ACTIN'''<br />
+
{{Structure
 +
|PDB= 1j6z |SIZE=350|CAPTION= <scene name='initialview01'>1j6z</scene>, resolution 1.54&Aring;
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=RHO:TETRAMETHYLRHODAMINE-5-MALEIMIDE'>RHO</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''UNCOMPLEXED ACTIN'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1J6Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=RHO:'>RHO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J6Z OCA].
+
1J6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J6Z OCA].
==Reference==
==Reference==
-
The crystal structure of uncomplexed actin in the ADP state., Otterbein LR, Graceffa P, Dominguez R, Science. 2001 Jul 27;293(5530):708-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11474115 11474115]
+
The crystal structure of uncomplexed actin in the ADP state., Otterbein LR, Graceffa P, Dominguez R, Science. 2001 Jul 27;293(5530):708-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11474115 11474115]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 23: Line 32:
[[Category: tetramethylrhodamine-5-maleimide]]
[[Category: tetramethylrhodamine-5-maleimide]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:19:21 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:59:25 2008''

Revision as of 09:59, 20 March 2008

Image:1j6z.gif


PDB ID 1j6z

Drag the structure with the mouse to rotate
, resolution 1.54Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



UNCOMPLEXED ACTIN


Overview

The dynamics and polarity of actin filaments are controlled by a conformational change coupled to the hydrolysis of adenosine 5'-triphosphate (ATP) by a mechanism that remains to be elucidated. Actin modified to block polymerization was crystallized in the adenosine 5'-diphosphate (ADP) state, and the structure was solved to 1.54 angstrom resolution. Compared with previous ATP-actin structures from complexes with deoxyribonuclease I, profilin, and gelsolin, monomeric ADP-actin is characterized by a marked conformational change in subdomain 2. The successful crystallization of monomeric actin opens the way to future structure determinations of actin complexes with actin-binding proteins such as myosin.

About this Structure

1J6Z is a Single protein structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

The crystal structure of uncomplexed actin in the ADP state., Otterbein LR, Graceffa P, Dominguez R, Science. 2001 Jul 27;293(5530):708-11. PMID:11474115

Page seeded by OCA on Thu Mar 20 11:59:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1j6z"
Personal tools