2e6a
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with orotate== | |
| - | + | <StructureSection load='2e6a' size='340' side='right' caption='[[2e6a]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[2e6a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6A FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene><br> |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2djl|2djl]], [[2djx|2djx]], [[2e68|2e68]], [[2e6d|2e6d]], [[2e6f|2e6f]]</td></tr> | |
| - | == | + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TCDHOD2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 Trypanosoma cruzi])</td></tr> |
| - | [[2e6a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6A OCA]. | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] </span></td></tr> |
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e6a RCSB], [http://www.ebi.ac.uk/pdbsum/2e6a PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6a_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | *[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Dihydroorotate oxidase]] | [[Category: Dihydroorotate oxidase]] | ||
[[Category: Trypanosoma cruzi]] | [[Category: Trypanosoma cruzi]] | ||
Revision as of 10:53, 3 October 2014
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with orotate
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Categories: Dihydroorotate oxidase | Trypanosoma cruzi | Aoki, T. | Harada, S. | Inaoka, D K. | Kita, K. | Kurisu, G. | Nara, T. | Sakamoto, K. | Shiba, T. | Shimizu, H. | Chagas disease | Dihydroorotate dehydrogenase | Energy metabolism | Flavoprotein | Fumarate reductase | Oxidoreductase | Pyrimidine biosynthesis | Redox homeostasis
