4aqy
From Proteopedia
(Difference between revisions)
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| - | ==Structure of | + | ==Structure of ribosome-apramycin complexes== |
<StructureSection load='4aqy' size='340' side='right' caption='[[4aqy]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='4aqy' size='340' side='right' caption='[[4aqy]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4aqy]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQY FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4aqy]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQY FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AM2:APRAMYCIN'>AM2</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AM2:APRAMYCIN'>AM2</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ab3|1ab3]], [[1an7|1an7]], [[1cqm|1cqm]], [[1cqn|1cqn]], [[1dv4|1dv4]], [[1eg0|1eg0]], [[1emw|1emw]], [[1fjg|1fjg]], [[1fka|1fka]], [[1gix|1gix]], [[1hnw|1hnw]], [[1hnx|1hnx]], [[1hnz|1hnz]], [[1hr0|1hr0]], [[1i94|1i94]], [[1i95|1i95]], [[1i96|1i96]], [[1i97|1i97]], [[1ibk|1ibk]], [[1ibl|1ibl]], [[1ibm|1ibm]], [[1j5e|1j5e]], [[1jgo|1jgo]], [[1jgp|1jgp]], [[1jgq|1jgq]], [[1kuq|1kuq]], [[1l1u|1l1u]], [[1lou|1lou]], [[1mvr|1mvr]], [[1n32|1n32]], [[1n33|1n33]], [[1n34|1n34]], [[1n36|1n36]], [[1pns|1pns]], [[1pnx|1pnx]], [[1qd7|1qd7]], [[1qjh|1qjh]], [[1qkf|1qkf]], [[1qkh|1qkh]], [[1ris|1ris]], [[1rss|1rss]], [[1twt|1twt]], [[1vox|1vox]], [[1voz|1voz]], [[1xmo|1xmo]], [[1xmq|1xmq]], [[1xnq|1xnq]], [[1xnr|1xnr]], [[1yl4|1yl4]], [[2b64|2b64]], [[2b9m|2b9m]], [[2b9o|2b9o]], [[2bvz|2bvz]], [[2bxj|2bxj]], [[2f4v|2f4v]], [[2j00|2j00]], [[2j02|2j02]], [[2jl7|2jl7]], [[2uu9|2uu9]], [[2uua|2uua]], [[2uub|2uub]], [[2uuc|2uuc]], [[2uxb|2uxb]], [[2uxc|2uxc]], [[2uxd|2uxd]], [[2v46|2v46]], [[2v48|2v48]], [[2vqe|2vqe]], [[2vqf|2vqf]], [[2wdg|2wdg]], [[2wdh|2wdh]], [[2wdk|2wdk]], [[2wdm|2wdm]], [[2wh1|2wh1]], [[2wh3|2wh3]], [[2wrn|2wrn]], [[2wrq|2wrq]], [[2x9r|2x9r]], [[2x9t|2x9t]], [[2xfz|2xfz]], [[2xg1|2xg1]], [[2xqd|2xqd]], [[2xsy|2xsy]], [[2xuy|2xuy]], [[2y0u|2y0u]], [[2y0w|2y0w]], [[2y0y|2y0y]], [[2y10|2y10]], [[2y12|2y12]], [[2y14|2y14]], [[2y18|2y18]], [[3zvo|3zvo]], [[4abr|4abr]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ab3|1ab3]], [[1an7|1an7]], [[1cqm|1cqm]], [[1cqn|1cqn]], [[1dv4|1dv4]], [[1eg0|1eg0]], [[1emw|1emw]], [[1fjg|1fjg]], [[1fka|1fka]], [[1gix|1gix]], [[1hnw|1hnw]], [[1hnx|1hnx]], [[1hnz|1hnz]], [[1hr0|1hr0]], [[1i94|1i94]], [[1i95|1i95]], [[1i96|1i96]], [[1i97|1i97]], [[1ibk|1ibk]], [[1ibl|1ibl]], [[1ibm|1ibm]], [[1j5e|1j5e]], [[1jgo|1jgo]], [[1jgp|1jgp]], [[1jgq|1jgq]], [[1kuq|1kuq]], [[1l1u|1l1u]], [[1lou|1lou]], [[1mvr|1mvr]], [[1n32|1n32]], [[1n33|1n33]], [[1n34|1n34]], [[1n36|1n36]], [[1pns|1pns]], [[1pnx|1pnx]], [[1qd7|1qd7]], [[1qjh|1qjh]], [[1qkf|1qkf]], [[1qkh|1qkh]], [[1ris|1ris]], [[1rss|1rss]], [[1twt|1twt]], [[1vox|1vox]], [[1voz|1voz]], [[1xmo|1xmo]], [[1xmq|1xmq]], [[1xnq|1xnq]], [[1xnr|1xnr]], [[1yl4|1yl4]], [[2b64|2b64]], [[2b9m|2b9m]], [[2b9o|2b9o]], [[2bvz|2bvz]], [[2bxj|2bxj]], [[2f4v|2f4v]], [[2j00|2j00]], [[2j02|2j02]], [[2jl7|2jl7]], [[2uu9|2uu9]], [[2uua|2uua]], [[2uub|2uub]], [[2uuc|2uuc]], [[2uxb|2uxb]], [[2uxc|2uxc]], [[2uxd|2uxd]], [[2v46|2v46]], [[2v48|2v48]], [[2vqe|2vqe]], [[2vqf|2vqf]], [[2wdg|2wdg]], [[2wdh|2wdh]], [[2wdk|2wdk]], [[2wdm|2wdm]], [[2wh1|2wh1]], [[2wh3|2wh3]], [[2wrn|2wrn]], [[2wrq|2wrq]], [[2x9r|2x9r]], [[2x9t|2x9t]], [[2xfz|2xfz]], [[2xg1|2xg1]], [[2xqd|2xqd]], [[2xsy|2xsy]], [[2xuy|2xuy]], [[2y0u|2y0u]], [[2y0w|2y0w]], [[2y0y|2y0y]], [[2y10|2y10]], [[2y12|2y12]], [[2y14|2y14]], [[2y18|2y18]], [[3zvo|3zvo]], [[4abr|4abr]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aqy RCSB], [http://www.ebi.ac.uk/pdbsum/4aqy PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aqy RCSB], [http://www.ebi.ac.uk/pdbsum/4aqy PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin.,Matt T, Ng CL, Lang K, Sha SH, Akbergenov R, Shcherbakov D, Meyer M, Duscha S, Xie J, Dubbaka SR, Perez-Fernandez D, Vasella A, Ramakrishnan V, Schacht J, Bottger EC Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10984-9. Epub 2012 Jun 14. PMID:22699498<ref>PMID:22699498</ref> | Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin.,Matt T, Ng CL, Lang K, Sha SH, Akbergenov R, Shcherbakov D, Meyer M, Duscha S, Xie J, Dubbaka SR, Perez-Fernandez D, Vasella A, Ramakrishnan V, Schacht J, Bottger EC Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10984-9. Epub 2012 Jun 14. PMID:22699498<ref>PMID:22699498</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Flavobacterium thermophilum yoshida and oshima 1971]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Akbergenov, R.]] | [[Category: Akbergenov, R.]] | ||
Revision as of 05:40, 8 October 2014
Structure of ribosome-apramycin complexes
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Categories: Flavobacterium thermophilum yoshida and oshima 1971 | Thermus thermophilus | Akbergenov, R. | Bottger, E C. | Dubbaka, S R. | Duscha, S. | Lang, K. | Matt, T. | Meyer, M. | Ng, C L. | Perez-Fernandez, D. | Ramakrishnan, V. | Schacht, J. | Sha, S H. | Shcherbakov, D. | Vasella, A. | Xie, J. | Apramycin | Ribosome | Toxicity
