1jdq

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[[Image:1jdq.jpg|left|200px]]<br /><applet load="1jdq" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1jdq.jpg|left|200px]]
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caption="1jdq" />
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'''Solution Structure of TM006 Protein from Thermotoga maritima'''<br />
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{{Structure
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|PDB= 1jdq |SIZE=350|CAPTION= <scene name='initialview01'>1jdq</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''Solution Structure of TM006 Protein from Thermotoga maritima'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1JDQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JDQ OCA].
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1JDQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JDQ OCA].
==Reference==
==Reference==
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An NMR approach to structural proteomics., Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH, Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11854485 11854485]
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An NMR approach to structural proteomics., Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH, Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11854485 11854485]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Kozlov, G.]]
[[Category: Kozlov, G.]]
[[Category: Yee, A.]]
[[Category: Yee, A.]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: thermotoga maritima]]
[[Category: thermotoga maritima]]
[[Category: tm006]]
[[Category: tm006]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:21:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:02:02 2008''

Revision as of 10:02, 20 March 2008


PDB ID 1jdq

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Solution Structure of TM006 Protein from Thermotoga maritima


Overview

The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMR. Although there was variability among proteomes, overall 20% of these proteins were found to be readily amenable to NMR structure determination. NMR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.

About this Structure

1JDQ is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

Reference

An NMR approach to structural proteomics., Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH, Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:11854485

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