243d

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[[Image:243d.png|left|200px]]
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==STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2==
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<StructureSection load='243d' size='340' side='right' caption='[[243d]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[243d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=243D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=243D FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=243d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=243d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=243d RCSB], [http://www.ebi.ac.uk/pdbsum/243d PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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d(ACGTACGT), C(78)H(84)N(30)O(32)P(7).20H(2)O, M(r) (DNA) = 2170, tetragonal, P4(3)2(1)2 (No 96), a = 42.845 (1), b = 42.845(1), c = 24.804 (1) A, V = 45532.5 (2) A(3), z = 8,lambda(MoKalpha) = 0.71069 A, micro (MoKalpha) = 0.10 mm(-1), T = 295 K, R = 0.18 for 1994 unique reflections between 5.0 and 1.9 A resolution. The self-complementary octanucleotide d(ACGTACGT)(2) has been crystallized and its structure determined to a resolution of 1.9 A. The asymmetric unit consists of a single strand of octamer with 20 water molecules. It is only the second example of an octanucleotide having terminal A.T base pairs whose structure has been determined by X-ray crystallography. The sequence adopts the modified A-type conformation found for all octanucleotide duplexes studied to date with the helix bent by approximately 15 degrees and an average tilt angle of 0 degrees. Unusually the data collection was carried out using a 3 kW molybdenum sealed-tube source. The conformational details are discussed in comparison with other closely related sequences.
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{{STRUCTURE_243d| PDB=243d | SCENE= }}
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Structure of the DNA octanucleotide d(ACGTACGT)2.,Wilcock DJ, Adams A, Cardin CJ, Wakelin LP Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):481-5. PMID:15299669<ref>PMID:15299669</ref>
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===STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15299669}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[243d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=243D OCA].
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</StructureSection>
[[Category: Adams, A.]]
[[Category: Adams, A.]]
[[Category: Cardin, C J.]]
[[Category: Cardin, C J.]]

Revision as of 08:15, 8 October 2014

STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2

243d, resolution 1.90Å

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