2d47

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[[Image:2d47.png|left|200px]]
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==MOLECULAR STRUCTURE OF A COMPLETE TURN OF A-DNA==
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<StructureSection load='2d47' size='340' side='right' caption='[[2d47]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2d47]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D47 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d47 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d47 RCSB], [http://www.ebi.ac.uk/pdbsum/2d47 PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We have determined the crystal structure of the dodecamer d(CCCCCGCGGGGG), showing for the first time a complete turn of A-DNA. It has average structural parameters similar to those determined in fibres. Nevertheless it shows a considerable local variation in structure which is in part associated with the presence of a bound spermine molecule. We conclude that the local DNA conformation does not only depend on the base sequence, but may be strongly modified upon interaction with other molecules. In particular, the CpG sequence, which is found in hypersensitive regions of the genome, appears to be able to easily change its conformation under external influences.
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{{STRUCTURE_2d47| PDB=2d47 | SCENE= }}
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Molecular structure of a complete turn of A-DNA.,Verdaguer N, Aymami J, Fernandez-Forner D, Fita I, Coll M, Huynh-Dinh T, Igolen J, Subirana JA J Mol Biol. 1991 Sep 20;221(2):623-35. PMID:1920437<ref>PMID:1920437</ref>
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===MOLECULAR STRUCTURE OF A COMPLETE TURN OF A-DNA===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_1920437}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2d47]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D47 OCA].
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</StructureSection>
[[Category: Aymami, J.]]
[[Category: Aymami, J.]]
[[Category: Coll, M.]]
[[Category: Coll, M.]]

Revision as of 08:20, 8 October 2014

MOLECULAR STRUCTURE OF A COMPLETE TURN OF A-DNA

2d47, resolution 2.00Å

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