1xok

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1xok" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:1xok.png|left|200px]]
+
==crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide==
 +
<StructureSection load='1xok' size='340' side='right' caption='[[1xok]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1xok]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XOK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XOK FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xok OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xok RCSB], [http://www.ebi.ac.uk/pdbsum/1xok PDBsum]</span></td></tr>
 +
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Alfalfa mosaic virus genomic RNAs are infectious only when the viral coat protein binds to the RNA 3' termini. The crystal structure of an alfalfa mosaic virus RNA-peptide complex reveals that conserved AUGC repeats and Pro-Thr-x-Arg-Ser-x-x-Tyr coat protein amino acids cofold upon interacting. Alternating AUGC residues have opposite orientation, and they base pair in different adjacent duplexes. Localized RNA backbone reversals stabilized by arginine-guanine interactions place the adenosines and guanines in reverse order in the duplex. The results suggest that a uniform, organized 3' conformation, similar to that found on viral RNAs with transfer RNA-like ends, may be essential for replication.
-
{{STRUCTURE_1xok| PDB=1xok | SCENE= }}
+
Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication.,Guogas LM, Filman DJ, Hogle JM, Gehrke L Science. 2004 Dec 17;306(5704):2108-11. PMID:15604410<ref>PMID:15604410</ref>
-
===crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_15604410}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[1xok]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XOK OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:015604410</ref><references group="xtra"/>
+
[[Category: Filman, D J.]]
[[Category: Filman, D J.]]
[[Category: Gehrke, L.]]
[[Category: Gehrke, L.]]

Revision as of 08:26, 8 October 2014

crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide

1xok, resolution 3.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xok"
Personal tools