1rau
From Proteopedia
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- | [[ | + | ==SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES== |
+ | <StructureSection load='1rau' size='340' side='right' caption='[[1rau]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[1rau]] is a 4 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RAU FirstGlance]. <br> | ||
+ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rau RCSB], [http://www.ebi.ac.uk/pdbsum/1rau PDBsum]</span></td></tr> | ||
+ | </table> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | A model for the solution structure of an RNA tetraplex, (rUGGGGU)4, has been obtained by two-dimensional NMR spectroscopy and molecular dynamics. The molecule is parallel stranded and Hoogsteen base-paired in 50 mM KCl, and it is so stable that three of its six imino protons have exchange half-lives measured in days at 40 degrees C. The tetraplex is stabilized by base stacking and by the hydrogen bonds in four G quartets and at least one U quartet. This is the first indication of the existence of U-quartet structures of which we are aware. | ||
- | + | Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures.,Cheong C, Moore PB Biochemistry. 1992 Sep 15;31(36):8406-14. PMID:1382577<ref>PMID:1382577</ref> | |
- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | + | </div> | |
- | + | == References == | |
- | + | <references/> | |
- | == | + | __TOC__ |
- | + | </StructureSection> | |
[[Category: Cheong, C.]] | [[Category: Cheong, C.]] | ||
[[Category: Moore, P B.]] | [[Category: Moore, P B.]] | ||
[[Category: Rna]] | [[Category: Rna]] | ||
[[Category: Tetraplex]] | [[Category: Tetraplex]] |
Revision as of 08:27, 8 October 2014
SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES
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Categories: Cheong, C. | Moore, P B. | Rna | Tetraplex