1yq8

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[[Image:1yq8.png|left|200px]]
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==PRD1 vertex protein P5==
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<StructureSection load='1yq8' size='340' side='right' caption='[[1yq8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1yq8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YQ8 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yq5|1yq5]], [[1yq6|1yq6]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yq8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yq8 RCSB], [http://www.ebi.ac.uk/pdbsum/1yq8 PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Comparisons of bacteriophage PRD1 and adenovirus protein structures and virion architectures have been instrumental in unraveling an evolutionary relationship and have led to a proposal of a phylogeny-based virus classification. The structure of the PRD1 spike protein P5 provides further insight into the evolution of viral proteins. The crystallized P5 fragment comprises two structural domains: a globular knob and a fibrous shaft. The head folds into a ten-stranded jelly roll beta barrel, which is structurally related to the tumor necrosis factor (TNF) and the PRD1 coat protein domains. The shaft domain is a structural counterpart to the adenovirus spike shaft. The structural relationships between PRD1, TNF, and adenovirus proteins suggest that the vertex proteins may have originated from an ancestral TNF-like jelly roll coat protein via a combination of gene duplication and deletion.
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{{STRUCTURE_1yq8| PDB=1yq8 | SCENE= }}
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The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture.,Merckel MC, Huiskonen JT, Bamford DH, Goldman A, Tuma R Mol Cell. 2005 Apr 15;18(2):161-70. PMID:15837420<ref>PMID:15837420</ref>
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===PRD1 vertex protein P5===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15837420}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1yq8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQ8 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015837420</ref><references group="xtra"/>
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[[Category: Enterobacteria phage prd1]]
[[Category: Enterobacteria phage prd1]]
[[Category: Bamford, D H.]]
[[Category: Bamford, D H.]]

Revision as of 08:31, 8 October 2014

PRD1 vertex protein P5

1yq8, resolution 2.60Å

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