2pyr

From Proteopedia

Revision as of 15:31, 30 October 2007

PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K)

Overview

Photoactive yellow protein (PYP) is a member of the xanthopsin family of, eubacterial blue-light photoreceptors. On absorption of light, PYP enters, a photocycle that ultimately transduces the energy contained in a light, signal into an altered biological response. Nanosecond time-resolved x-ray, crystallography was used to determine the structure of the short-lived, red-shifted, intermediate state denoted [pR], which develops within 1, nanosecond after photoelectronic excitation of the chromophore of PYP by, absorption of light. The resulting structural model demonstrates that the, [pR] state possesses the cis conformation of the 4-hydroxyl cinnamic, thioester chromophore, and that the process of trans to cis isomerization, is accompanied by the specific formation of new hydrogen bonds ... [(full description)]

About this Structure

2PYR is a [Single protein] structure of sequence from [Halorhodospira halophila] with HC4 as [ligand]. Structure known Active Site: CRE. Full crystallographic information is available from [OCA].

Reference

Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle., Perman B, Srajer V, Ren Z, Teng T, Pradervand C, Ursby T, Bourgeois D, Schotte F, Wulff M, Kort R, Hellingwerf K, Moffat K, Science. 1998 Mar 20;279(5358):1946-50. PMID:9506946

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