4ux6
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ux6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ux6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ux6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ux6 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ux6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ux6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ux6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ux6 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | By careful analysis of experimental X-ray ligand crystallographic protein data across several inhibitor series we have discovered a novel, potent and selective series of iNOS inhibitors exemplified by compound 8. | ||
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| + | The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).,Cheshire DR, Berg A, Andersson GM, Andrews G, Beaton HG, Birkinshaw TN, Boughton-Smith N, Connolly S, Cook TR, Cooper A, Cooper SL, Cox D, Dixon J, Gensmantel N, Hamley PJ, Harrison R, Hartopp P, Kack H, Leeson PD, Luker T, Mete A, Millichip I, Nicholls DJ, Pimm AD, St-Gallay SA, Wallace AV Bioorg Med Chem Lett. 2011 Apr 15;21(8):2468-71. Epub 2011 Feb 18. PMID:21398123<ref>PMID:21398123</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:37, 20 October 2014
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
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Categories: Andrews, G. | Beaton, H G. | Birkinshaw, T. | Boughton-Smith, N. | Cheshire, D R. | Connolly, S. | Cook, T R. | Cooper, A. | Cooper, S L. | Cox, D. | Dixon, J. | Gensmantel, N. | Hamley, P J. | Harrison, R. | Hartopp, P. | Kack, H. | Luker, T. | Mete, A. | Millichip, I. | Nicholls, D J. | Pimm, A D. | St-Gallay, S A. | Wallace, A V. | Drug design | Oxidoreductase
