This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4rb9
From Proteopedia
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites== |
| - | + | <StructureSection load='4rb9' size='340' side='right' caption='[[4rb9]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rb9]] is a 25 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RB9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RB9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCY:PACTAMYCIN'>PCY</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=MIA:2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5-MONOPHOSPHATE'>MIA</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rba|4rba]], [[4rbb|4rbb]], [[4rbc|4rbc]]</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rb9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rb9 RCSB], [http://www.ebi.ac.uk/pdbsum/4rb9 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Thermus thermophilus]] | ||
| + | [[Category: Bogdanov, A A.]] | ||
| + | [[Category: Bulkley, D.]] | ||
| + | [[Category: Dontsova, O A.]] | ||
| + | [[Category: Efimenko, T A.]] | ||
| + | [[Category: Efremenkova, O V.]] | ||
| + | [[Category: Konevega, A L.]] | ||
| + | [[Category: Kusochek, P.]] | ||
| + | [[Category: Malanicheva, I A.]] | ||
| + | [[Category: Mankin, A S.]] | ||
| + | [[Category: Osterman, I A.]] | ||
| + | [[Category: Polikanov, Y S.]] | ||
| + | [[Category: Rodnina, M V.]] | ||
| + | [[Category: Serebryakova, M V.]] | ||
| + | [[Category: Sergiev, P V.]] | ||
| + | [[Category: Shaw, K J.]] | ||
| + | [[Category: Steitz, T A.]] | ||
| + | [[Category: Szal, T.]] | ||
| + | [[Category: Tashlitsky, V N.]] | ||
| + | [[Category: 50s subunit of the 1st 70s ribosome in the asu]] | ||
| + | [[Category: 70s ribosome]] | ||
| + | [[Category: And e-site trnas of the 1st 70s ribosome in the asu]] | ||
| + | [[Category: Antibiotic]] | ||
| + | [[Category: Deacylated a-]] | ||
| + | [[Category: Inhibition of translation]] | ||
| + | [[Category: Initiation inhibitor]] | ||
| + | [[Category: Mrna]] | ||
| + | [[Category: P-]] | ||
| + | [[Category: Pactamycin]] | ||
| + | [[Category: Ribosome-antibiotic complex]] | ||
Revision as of 10:59, 20 October 2014
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites
| |||||||||||
Categories: Thermus thermophilus | Bogdanov, A A. | Bulkley, D. | Dontsova, O A. | Efimenko, T A. | Efremenkova, O V. | Konevega, A L. | Kusochek, P. | Malanicheva, I A. | Mankin, A S. | Osterman, I A. | Polikanov, Y S. | Rodnina, M V. | Serebryakova, M V. | Sergiev, P V. | Shaw, K J. | Steitz, T A. | Szal, T. | Tashlitsky, V N. | 50s subunit of the 1st 70s ribosome in the asu | 70s ribosome | And e-site trnas of the 1st 70s ribosome in the asu | Antibiotic | Deacylated a- | Inhibition of translation | Initiation inhibitor | Mrna | P- | Pactamycin | Ribosome-antibiotic complex
