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2w8m

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[[Image:2w8m.png|left|200px]]
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==STRUCTURE OF D212, A NUCLEASE FROM A FUSSELOVIRUS.==
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<StructureSection load='2w8m' size='340' side='right' caption='[[2w8m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2w8m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_ragged_hills Sulfolobus virus ragged hills]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W8M FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w8m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w8m RCSB], [http://www.ebi.ac.uk/pdbsum/2w8m PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Structural studies have made significant contributions to our understanding of Sulfolobus spindle-shaped viruses (Fuselloviridae), an important model system for archaeal viruses. Continuing these efforts, we report the structure of D212 from Sulfolobus spindle-shaped virus Ragged Hills. The overall fold and conservation of active site residues place D212 in the PD-(D/E)XK nuclease superfamily. The greatest structural similarity is found to the archaeal Holliday junction cleavage enzymes, strongly suggesting a role in DNA replication, repair, or recombination. Other roles associated with nuclease activity are also considered.
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{{STRUCTURE_2w8m| PDB=2w8m | SCENE= }}
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The crystal structure of D212 from sulfolobus spindle-shaped virus ragged hills reveals a new member of the PD-(D/E)XK nuclease superfamily.,Menon SK, Eilers BJ, Young MJ, Lawrence CM J Virol. 2010 Jun;84(12):5890-7. Epub 2010 Apr 7. PMID:20375162<ref>PMID:20375162</ref>
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===STRUCTURE OF D212, A NUCLEASE FROM A FUSSELOVIRUS.===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_20375162}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2w8m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_ragged_hills Sulfolobus virus ragged hills]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8M OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:020375162</ref><references group="xtra"/>
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[[Category: Sulfolobus virus ragged hills]]
[[Category: Sulfolobus virus ragged hills]]
[[Category: Lawrence, C M.]]
[[Category: Lawrence, C M.]]

Revision as of 11:34, 20 October 2014

STRUCTURE OF D212, A NUCLEASE FROM A FUSSELOVIRUS.

2w8m, resolution 2.40Å

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