3zyt

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<StructureSection load='3zyt' size='340' side='right' caption='[[3zyt]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='3zyt' size='340' side='right' caption='[[3zyt]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zyt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_nitroguajacolicus Arthrobacter nitroguajacolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZYT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zyt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Artnt Artnt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZYT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zyt RCSB], [http://www.ebi.ac.uk/pdbsum/3zyt PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zyt RCSB], [http://www.ebi.ac.uk/pdbsum/3zyt PDBsum]</span></td></tr>
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<table>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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In this article we analyze the reasons for catalytic promiscuity of a type VIII esterase with beta-lactamase fold and the ability to cleave beta-lactams. We compared the structure of this enzyme to those of an esterase of the same type without any lactamase ability, an esterase with moderate lactamase ability, and a class C beta-lactamase with similar fold. Our results show that for these enzymes, the difference in the substrate specificity is sterically driven.
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Crystal structure analysis of EstA from Arthrobacter sp. Rue61a--an insight into catalytic promiscuity.,Wagner UG, DiMaio F, Kolkenbrock S, Fetzner S FEBS Lett. 2014 Apr 2;588(7):1154-60. doi: 10.1016/j.febslet.2014.02.045. Epub, 2014 Mar 5. PMID:24613918<ref>PMID:24613918</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arthrobacter nitroguajacolicus]]
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[[Category: Artnt]]
[[Category: Fetzner, S.]]
[[Category: Fetzner, S.]]
[[Category: Wagner, U G.]]
[[Category: Wagner, U G.]]

Revision as of 08:45, 22 October 2014

Structure Determination of EstA from Arthrobacter nitroguajacolicus Rue61a

3zyt, resolution 2.45Å

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