1jx7

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[[Image:1jx7.gif|left|200px]]<br /><applet load="1jx7" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1jx7.gif|left|200px]]
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caption="1jx7, resolution 2.80&Aring;" />
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'''Crystal structure of ychN protein from E.coli'''<br />
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{{Structure
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|PDB= 1jx7 |SIZE=350|CAPTION= <scene name='initialview01'>1jx7</scene>, resolution 2.80&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''Crystal structure of ychN protein from E.coli'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1JX7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JX7 OCA].
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1JX7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JX7 OCA].
==Reference==
==Reference==
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Crystal structure of a conserved hypothetical protein from Escherichia coli., Shin DH, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(1):53-66. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12836674 12836674]
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Crystal structure of a conserved hypothetical protein from Escherichia coli., Shin DH, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(1):53-66. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12836674 12836674]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:27:48 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:09:40 2008''

Revision as of 10:09, 20 March 2008


PDB ID 1jx7

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, resolution 2.80Å
Coordinates: save as pdb, mmCIF, xml



Crystal structure of ychN protein from E.coli


Overview

The crystal structure of a conserved hypothetical protein from Escherichia coli has been determined using X-ray crystallography. The protein belongs to the Cluster of Orthologous Group COG1553 (National Center for Biotechnology Information database, NLM, NIH), for which there was no structural information available until now. Structural homology search with DALI algorism indicated that this protein has a new fold with no obvious similarity to those of other proteins with known three-dimensional structures. The protein quaternary structure consists of a dimer of trimers, which makes a characteristic cylinder shape. There is a large closed cavity with approximate dimensions of 16 A x 16 A x 20 A in the center of the hexameric structure. Six putative active sites are positioned along the equatorial surface of the hexamer. There are several highly conserved residues including two possible functional cysteines in the putative active site. The possible molecular function of the protein is discussed.

About this Structure

1JX7 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of a conserved hypothetical protein from Escherichia coli., Shin DH, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(1):53-66. PMID:12836674

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