1jy5

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[[Image:1jy5.gif|left|200px]]<br /><applet load="1jy5" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1jy5.gif|left|200px]]
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caption="1jy5, resolution 2.05&Aring;" />
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'''RNase-related protein from Calystegia sepium'''<br />
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{{Structure
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|PDB= 1jy5 |SIZE=350|CAPTION= <scene name='initialview01'>1jy5</scene>, resolution 2.05&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''RNase-related protein from Calystegia sepium'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1JY5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Calystegia_sepium Calystegia sepium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JY5 OCA].
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1JY5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Calystegia_sepium Calystegia sepium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JY5 OCA].
==Reference==
==Reference==
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Structure of an RNase-related protein from Calystegia sepium., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):627-33. Epub 2002, Mar 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11914487 11914487]
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Structure of an RNase-related protein from Calystegia sepium., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):627-33. Epub 2002, Mar 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11914487 11914487]
[[Category: Calystegia sepium]]
[[Category: Calystegia sepium]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: rnase]]
[[Category: rnase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:27:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:10:02 2008''

Revision as of 10:10, 20 March 2008

Image:1jy5.gif


PDB ID 1jy5

Drag the structure with the mouse to rotate
, resolution 2.05Å
Coordinates: save as pdb, mmCIF, xml



RNase-related protein from Calystegia sepium


Overview

The structure of a catalytically inactive RNase-related protein from Calystegia sepium (CalsepRRP) has been resolved by protein crystallography at a resolution of 2.05 A and an R factor of 20.74%. Although the protein is completely devoid of ribonuclease activity, it adopts the typical alpha + beta structure of non-base-specific RNases. Analysis of the structure revealed that two amino-acid substitutions in the 'active' P1 site, in combination with the less hydrophobic/aromatic character of the B1 base-recognition site and a completely disrupted B2 base-recognition site, might account for this complete lack of activity.

About this Structure

1JY5 is a Single protein structure of sequence from Calystegia sepium. Full crystallographic information is available from OCA.

Reference

Structure of an RNase-related protein from Calystegia sepium., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):627-33. Epub 2002, Mar 22. PMID:11914487

Page seeded by OCA on Thu Mar 20 12:10:02 2008

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